There are numerous benefits of fasting and fasting-mimicking diets. Below are a number of resources that you can explore to learn more about the benefits of fasting and fasting-mimicking diets and the health benefits of these protocols.
Sip Kitchen’s Longevity Fasting Diet protocol is based on research from Dr. Valter Longo and his team at the University of Southern California (USC) Longevity Institute. Below are a variety of podcasts and resources on this research by Dr. Valter Longo. If you are interested in learning more about this research, explore the resources below.
Learn more about Dr. Valter Longo and his research on longevity
Fasting and Autoimmune Diseases
Choi, I.Y., C. Lee, and V.D. Longo, Nutrition and fasting-mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence. Mol Cell Endocrinol, 2017.
Fasting and Aging, Diabetes, Cancer, and Cardiovascular Disease
Wei, M., et al., Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Sci Transl Med, 2017. 9(377).
Fasting and Inflammatory Bowel Disease
Rangan et al., Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology. Cell Rep, 2019. 26(10): 2704–2719
Fasting and Cancer
1. Dr Valter Longo and the FMD
Research on the Fasting Mimicking Diet and Dr Valter Longo’s (Professor of Gerontology and Biological Sciences, Director of the Longevity Institute & founder of the FMD) recommendations.
2. Fasting and breast cancer
Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
This study indicated that a fasting-mimicking diet is safe and effective as an adjunct to chemotherapy in women with early breast cancer.
3. Fasting and cancer - general overview
Fasting mimicking diets and gut health
A study on a four-day fasting-mimicking diet and gut health showed that the FMD reduced intestinal inflammation, increased stem cell number, stimulated protective gut microbiota, and reversed intestinal pathology caused by DSS in those with Inflammatory Bowel Disease.
Benefits of Shorter Fasts and Intermittent Fasting
Animal studies have documented robust and replicable effects of fasting on health indicators including greater insulin sensitivity and reduced levels of blood pressure, body fat, IGF-I, insulin, glucose, atherogenic lipids, and inflammation. Fasting regimens can ameliorate disease processes and improve functional outcome in animal models of disorders that include cancer, myocardial infarction, diabetes, stroke, AD, and PD.
- V.D Longo and M.P Mattson, Fasting: Molecular Mechanisms and Clinical Applications, Cell Metabolism, 2014. 19 (2): 181-192
Low Protein Intake & IGF-1, Cancer, and Overall Mortality
- M. Levine et al., Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population, Cell Metabolism, 2014. 19 (3): 407-417